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Citrulline and arginine — nitric oxide (NO) precursors. NO dilates blood vessels, increasing blood flow to muscles, which translates into the visible "pump" effect during training — muscles appear fuller, working harder, with better nutrient delivery.
Key choice: citrulline is more effective than arginine. Arginine breaks down largely in the gut before reaching the bloodstream. Citrulline passes through the gut intact, then converts to arginine in the kidneys — ultimately producing more nitric oxide.
When choosing nitric oxide supplements, understanding form, dose, and timing strategy is key.
Direct arginine supplementation — less effective than citrulline. Absorption issues in the gut. If you want arginine — AAKG (Arginine Alpha-Ketoglutarate) is a more stable form.
Pump (the visible muscle fullness during training) is the result of more intense blood flow into muscle. Practical benefits: better mind-muscle connection, more intense sensation, psychological edge for motivation. Not a direct long-term muscle growth effect — pump disappears within 30 minutes post-workout. However, more intense training ultimately connects to growth.
Citrulline Malate 500g powder: 50-100 GEL (60 servings of 8g). L-Citrulline: 60-120 GEL for 500g. L-Arginine: 30-60 GEL. Pre-workout formulas often already contain 3-6g citrulline — money can be saved with a complete pre-workout.